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| Ladwig,R.; Vigo,A.; Fedeli,L.M.G.; Chambless,L.E.; Bensenor,I.; Schmidt,M.I.; Vidigal,P.G.; Castilhos,C.D.; Duncan,B.B.. |
| Multi-center epidemiological studies must ascertain that their measurements are accurate and reliable. For laboratory measurements, reliability can be assessed through investigation of reproducibility of measurements in the same individual. In this paper, we present results from the quality control analysis of the baseline laboratory measurements from the ELSA-Brasil study. The study enrolled 15,105 civil servants at 6 research centers in 3 regions of Brazil between 2008–2010, with multiple biochemical analytes being measured at a central laboratory. Quality control was ascertained through standard laboratory evaluation of intra- and inter-assay variability and test-retest analysis in a subset of randomly chosen participants. An additional sample of urine... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Multi-center studies; Laboratory measurements; Quality control. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000900701 |
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